Polymer/Polyoxometalate Smart Coatings For Chemical And Biological Applications (POCHBA)
POCHBA–Polymer/Polyoxometalate Smart Coatings For Chemical And Biological Applications
Combination of organic and inorganic components can lead to hybrid materials with unusual structures and properties originating from synergism between fractions. The appropriate choice of components can allow the resulting material to be processed as smart, stimuli-responsive coatings for applications as sensors-actuators in microelectronics, electrooptics and/or biotechnology, among others.
In this project we propose to prepare smart hybrid surfaces using polymers able to immobilize polyoxometalates (POMs).
Such surfaces will be synthetized onto magnetic substrates, either nanoparticles or magnetoelastic resonators, that allow to contacless monitor the system about its mass, so it will be possible to know the evolution of the surface during the synthesis as well as in the interaction with other molecules/systems and evaluate, therefore, their performance as sensors.
Hybrid materials will be prepared by anchoring POMs onto smart functionalized polymer surfaces having inter-polymer complexes. We pretend to prepare surfaces and coatings based on polystyrene and an amphiphilic diblock copolymer: PS-b-PX (PX= PEG, PLys or PAA). These polymeric surfaces can be formed or destroyed depending on environmental conditions and interact with other polymers or chemical species, and in particular, with POMs. Those are anionic metaloxo clusters that have been regarded as remarkable inorganic building blocks because of their multifunctional nature and have the possibility of anchoring on the above polymeric surfaces either through the coordination sphere of one of their metals, or through formation of extensive hydrogen-bonding networks.
The so prepared devices will be tested as drug delivery systems (isoPOMs grafted on PX = PAA or PLys functions) or as chemical sensors (heteroPOMs grafted on PX = PAA, PLys or PEG functions) after deposited onto Magnetic Nanoparticles or Magnetoelastic cantilever resonators, that act as vectors or detectors of the specific actuation respectively. The final aim of the project is to develop a demonstrator of a sensor based on these compounds.
Inorganic synthesis, single crystal x-ray diffaction